Early Detection of Cognitive Impairment: NIH Toolbox Cognitive Function Battery
  
   Lead Investigator:    Kathleen Welsh-Bohmer
   Institution      :    Duke
   E-Mail           :    kathleen.welshbohmer@duke.edu
   Proposal ID      :    198



   Proposal Description:
   Abstract: This is a revision of the proposal we submitted last year. The revision addresses many of the reviewers helpful comments. We intend to compare the NIH Toolbox CFB with paper and pencil tests in two groups of research participants, namely healthy controls and individuals with MCI (CDR=0.5). We will specifically determine sensitivity and specificity of these measures in correctly classifying the two groups. We will also investigate the relationship between test performance and other variables collected via the UDS, including ApoE status, age, and education, among others.